Highly diastereoselective synthesis of modified nucleosides via an asymmetric multicomponent reaction
نویسندگان
چکیده
منابع مشابه
Highly diastereoselective synthesis of modified nucleosides via an asymmetric multicomponent reaction.
We have developed a practical synthesis of unique nucleoside derivatives via TiCl(4) promoted multicomponent reaction of optically active dihydrofuran, ethyl pyruvate/glyoxylate, and a TMS protected nucleobase in a single-pot operation.
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ژورنال
عنوان ژورنال: Chemical Communications
سال: 2010
ISSN: 1359-7345,1364-548X
DOI: 10.1039/b924807b